International Scholarly Research Notices / 2013 / Article / Tab 8

Research Article

Examination of the Anti-Inflammatory, Antioxidant, and Xenobiotic-Inducing Potential of Broccoli Extract and Various Essential Oils during a Mild DSS-Induced Colitis in Rats

Table 8

Effects of feeding broccoli extract and various essential oils on relative mRNA expression of various pro- and anti-inflammatory parameters in colon of DSS-treated rats compared to an untreated control. Values are means ± SEM and represent relative mRNA concentrations as -fold of group Con = 1. Different small letters in a row indicate significant differences between means ( ≤ 0.05). in phase 1, in phase 2 and phase 3.

ColonExperimental group
PeriodConDSSBECuoToRo
GeneMWSEMMWSEMMWSEMMWSEMMWSEMMWSEM

Phase 11.000.530.560.101.040.100.560.211.170.70
NF BPhase 21.000.201.030.300.360.021.000.442.211.370.510.10
Phase 31.00a0.073.05b1.231.52ab0.281.31ab0.301.09ab0.161.51ab0.42
Phase 11.000.450.310.050.380.120.420.150.410.14
TNF Phase 21.00a0.153.96ab1.483.84ab1.281.65ab0.594.72b1.492.98ab0.76
Phase 31.00a0.183.71b0.854.56b0.973.75b0.784.18b1.083.34b0.90
Phase 11.000.810.130.030.900.400.550.290.960.61
COX2Phase 21.00ac0.3517.7b10.262.43ac1.001.68ac0.713.59bc1.101.25ac0.42
Phase 31.000.171.310.551.410.340.870.271.100.331.000.21
Phase 11.000.101.480.521.720.451.010.411.600.52
IL-1βPhase 21.000.331.100.341.700.821.210.360.520.221.170.29
Phase 31.00a0.334.69b1.402.32ab0.530.96a0.222.26a1.011.77a1.02
Phase 11.000.432.141.461.950.582.311.282.231.04
IL-10Phase 21.00a0.391.23ab0.351.46ab0.312.79b0.6522.5b15.033.79c1.50
Phase 3n.d.n.d.n.d.n.d.n.d.n.d.
Phase 11.000.120.880.090.940.041.460.451.040.23
MCP-1Phase 21.00a0.221.51ab0.202.20b0.301.67b0.152.76b0.562.03b0.58
Phase 31.00a0.272.60bc0.473.54b0.981.10a0.230.86a0.261.67ac0.57
Phase 11.00a0.420.43ab0.060.34b0.100.41b0.140.38b0.21
VCAM-1Phase 21.00ab0.462.40a1.180.39b0.190.39b0.130.62b0.250.66ab0.42
Phase 31.00a0.356.21b2.204.56b0.531.97a1.141.61a0.791.07a0.53
Phase 11.00a0.311.03a0.191.71ab0.201.63ab0.142.37b0.75
Cldn3Phase 21.00a0.380.57ab0.210.22b0.080.49ab0.220.25b0.210.25b0.07
Phase 31.00a0.181.46ab0.340.92a0.061.07a0.121.98b0.361.24a0.30

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