International Scholarly Research Notices / 2013 / Article / Tab 9

Research Article

Examination of the Anti-Inflammatory, Antioxidant, and Xenobiotic-Inducing Potential of Broccoli Extract and Various Essential Oils during a Mild DSS-Induced Colitis in Rats

Table 9

Effects of feeding broccoli extract and various essential oils on relative mRNA expression of various pro- and anti-inflammatory parameters in the liver of DSS-treated rats compared to an untreated control. Values are means ± SEM and represent relative mRNA concentrations as -fold of group Con = 1. Different small letters in a row indicate significant differences between means ( ≤ 0.05). in phase 1, in phase 2 and phase 3.

LiverExperimental group
GenePeriodConDSSBECuoToRo
MWSEMMWSEMMWSEMMWSEMMWSEMMWSEM

Phase 11.000.151.060.110.990.061.030.060.970.08
NF BPhase 21.000.060.940.070.990.030.990.051.020.071.020.06
Phase 31.000.040.960.031.000.030.990.041.070.051.060.06
Phase 11.000.171.040.071.060.120.900.031.100.06
TNF Phase 21.000.131.010.140.890.151.040.150.920.140.820.08
Phase 31.00a0.041.71b0.371.06ab0.121.14ab0.171.16ab0.111.55ab0.25
Phase 11.00abc0.150.81ab0.091.02ac0.060.75b0.151.12c0.06
COX2Phase 21.000.111.160.201.190.121.340.271.500.251.130.12
Phase 3n.d.n.d.n.d.n.d.n.d.n.d.
Phase 11.000.201.000.151.020.160.870.101.130.12
IL-1βPhase 21.000.111.040.110.930.121.010.141.120.100.980.08
Phase 31.00a0.030.95a0.080.85ab0.070.84ab0.060.75b0.051.01ab0.06
Phase 11.00a0.190.67b0.110.56b0.080.70ab0.150.68b0.08
IL-10Phase 21.000.120.770.101.150.251.060.151.060.091.010.09
Phase 31.00a0.060.76b0.050.79b0.080.67b0.060.69b0.030.77b0.03
Phase 11.00a0.051.25ab0.171.13a0.111.18a0.251.78b0.23
MCP-1Phase 21.000.121.000.071.080.151.200.111.120.171.190.13
Phase 31.000.071.010.121.000.100.960.111.000.101.010.03
Phase 11.00a0.200.74b0.080.80ab0.020.85ab0.070.91ab0.06
VCAM-1Phase 21.000.071.060.120.850.100.980.021.090.070.890.05
Phase 31.000.050.890.081.020.111.070.110.920.081.030.09
Phase 11.000.191.020.300.850.150.910.220.650.07
CRPPhase 21.000.201.070.210.740.050.930.200.850.101.140.15
Phase 31.00a0.110.87a0.111.37b0.210.89a0.100.87a0.120.73a0.06

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