International Scholarly Research Notices

Research Article

Quality by Design Approach for the Development and Validation of Glipizide, an Antidiabetic Drug, by RP-UPLC with Application to Formulated Forms and Urine

Figure 3

Method optimization at different pH conditions.
738397.fig.003a
(a) ACN: buffer (pH 3.5) (40 : 60% v/v)
738397.fig.003b
(b) ACN: buffer (pH 4.0) (20 : 80% v/v)
738397.fig.003c
(c) ACN: buffer (pH 2.2) (20 : 80% v/v)
738397.fig.003d
(d) ACN: buffer (pH 5.5) (20 : 80% v/v)