Research Article

Quality by Design Approach for the Development and Validation of Glipizide, an Antidiabetic Drug, by RP-UPLC with Application to Formulated Forms and Urine

Table 9

Results of recovery study by standard addition method.

Tablet studiedGPZ µg mL−1, tabletGPZ µg mL−1, pureTotal GPZ found, µg mL−1Percent recovery of pure GPZ,
(% GPZ ± SD)

Dibizide49.2150100.23101.03 ± 0.36
49.21150199.93100.36 ± 0.45
49.21250301.87100.89 ± 0.89

Glynase48.675099.89101.24 ± 1.12
48.67150201.23101.29 ± 0.1.02
48.67250302.23101.19 ± 0.98