Table of Contents
ISRN Ophthalmology
Volume 2013 (2013), Article ID 752161, 4 pages
http://dx.doi.org/10.1155/2013/752161
Research Article

Migration, Integration, Survival, and Differentiation of Stem Cell-Derived Neural Progenitors in the Retina in a Pharmacological Model of Retinal Degeneration

Vision Institute, Department of Ophthalmology, Federal University of São Paulo, 04021-001 São Paulo, SP, Brazil

Received 27 December 2012; Accepted 23 January 2013

Academic Editors: M. P. Shanmugam and H. Tomita

Copyright © 2013 Gustavo Castro et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. R. E. MacLaren, R. A. Pearson, A. MacNeil et al., “Retinal repair by transplantation of photoreceptor precursors,” Nature, vol. 444, no. 7116, pp. 203–207, 2006. View at Publisher · View at Google Scholar · View at Scopus
  2. H. Klassen, D. S. Sakaguchi, and M. J. Young, “Stem cells and retinal repair,” Progress in Retinal and Eye Research, vol. 23, no. 2, pp. 149–181, 2004. View at Publisher · View at Google Scholar · View at Scopus
  3. J. S. Meyer, M. L. Katz, J. A. Maruniak, and M. D. Kirk, “Embryonic stem cell-derived neural progenitors incorporate into degenerating retina and enhance survival of host photoreceptors,” Stem Cells, vol. 24, no. 2, pp. 274–283, 2006. View at Publisher · View at Google Scholar · View at Scopus
  4. M. J. Young, J. Ray, S. J. O. Whiteley, H. Klassen, and F. H. Gage, “Neuronal differentiation and morphological integration of hippocampal progenitor cells transplanted to the retina of immature and mature dystrophic rats,” Molecular and Cellular Neurosciences, vol. 16, no. 3, pp. 197–205, 2000. View at Publisher · View at Google Scholar · View at Scopus
  5. J. C. Huang, M. Ishida, P. Hersh, I. K. Sugino, and M. A. Zarbin, “Preparation and transplantation of photoreceptor sheets,” Current Eye Research, vol. 17, no. 6, pp. 573–585, 1998. View at Publisher · View at Google Scholar · View at Scopus
  6. A. Nishida, M. Takahashi, H. Tanihara et al., “Incorporation and differentiation of hippocampus-derived neural stem cells transplanted in injured adult rat retina,” Investigative Ophthalmology and Visual Science, vol. 41, no. 13, pp. 4268–4274, 2000. View at Google Scholar · View at Scopus
  7. K. Canola and Y. Arsenijevic, “Generation of cells committed towards the photoreceptor fate for retinal transplantation,” NeuroReport, vol. 18, no. 9, pp. 851–855, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. T. V. Johnson, N. D. Bull, and K. R. Martin, “Transplantation prospects for the inner retina,” Eye, vol. 23, no. 10, pp. 1980–1984, 2009. View at Publisher · View at Google Scholar · View at Scopus
  9. B. L. K. Coles, B. Angénieux, T. Inoue et al., “Facile isolation and the characterization of human retinal stem cells,” Proceedings of the National Academy of Sciences of the United States of America, vol. 101, no. 44, pp. 15772–15777, 2004. View at Publisher · View at Google Scholar · View at Scopus
  10. C. N. Svendsen, M. A. Caldwell, and T. Ostenfeld, “Human neural stem cells: Isolation, expansion and transplantation,” Brain Pathology, vol. 9, no. 3, pp. 499–513, 1999. View at Google Scholar · View at Scopus
  11. T. V. Johnson, N. D. Bull, D. P. Hunt, N. Marina, S. I. Tomarev, and K. R. Martin, “Neuroprotective effects of intravitreal mesenchymal stem cell transplantation in experimental glaucoma,” Investigative Ophthalmology and Visual Science, vol. 51, no. 4, pp. 2051–2059, 2010. View at Publisher · View at Google Scholar · View at Scopus
  12. A. Dahlmann-Noor, S. Vijay, H. Jayaram, A. Limb, and P. T. Khaw, “Current approaches and future prospects for stem cell rescue and regeneration of the retina and optic nerve,” Canadian Journal of Ophthalmology, vol. 45, no. 4, pp. 333–341, 2010. View at Publisher · View at Google Scholar · View at Scopus