Table of Contents
ISRN Inorganic Chemistry
Volume 2013 (2013), Article ID 760754, 7 pages
http://dx.doi.org/10.1155/2013/760754
Research Article

Synthesis, Structural Characterization, and Antimicrobial Activity Evaluation of New Binuclear Niobium(V) Tartrate Complexes with Biologically Important Drugs

1Department of Chemistry, University of Mysore, Manasagangotri, Mysore 570006, India
2Department of Chemistry, University of BDT College of Engineering, Davanagere University, Davanagere 577004, India

Received 31 October 2012; Accepted 27 November 2012

Academic Editors: A. Karadag, A. Lehtonen, and M. Pellei

Copyright © 2013 H. D. Revanasiddappa et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

The new binuclear niobium(V) complexes of the type [[NbO(L)C4H4O6]2C4H4O6] (where L = DMH, IMH, IPH, FPH, TMT) were prepared with biologically important drugs and characterized by using elemental analysis; IR, 1H-NMR, and UV-Vis spectral studies, and thermogravimetric analysis. The molar conductance measurement of all the complexes in DMF solution corresponds to 1 : 1 electrolytic nature. All complexes were of the pure diamagnetic character and were found to have six-coordinate octahedral geometry. The antimicrobial activity of these complexes has been screened against two Gram-positive and two Gram-negative bacteria. Antifungal activity against two different fungi has been evaluated and compared with controls. All the complexes inhibit the growth of both Gram-positive and Gram-negative bacteria to a competent level.