ERG Protein Expression Is of Limited Prognostic Value in Men with Localized Prostate Cancer

<table>(a) Prostate cancer Gleason score 6, negative for ERG expression. Note that endothelial cells acting as positive control show strong ERG expression. (b) Prostate cancer Gleason score 6, showing weak intensity ERG expression. (c) Prostate cancer Gleason score 7 (<svg height="11.125" id="M18" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 33.974998 11.125" width="33.974998" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,10.862)"><path d="M285 378v-2q65 -13 102 -54.5t37 -97.5q0 -57 -30.5 -104.5t-74 -75t-85.5 -42t-72 -14.5q-31 0 -59.5 11t-40.5 23q-19 18 -16 36q1 16 23 33q13 10 24 0q58 -51 124 -51q55 0 88 40t33 112q0 64 -39 96.5t-88 32.5q-29 0 -64 -11l-6 29q77 25 118 57.5t41 84.5
q0 45 -26.5 69.5t-68.5 24.5q-67 0 -120 -79l-20 20l43 63q51 56 127 56h1q66 0 107 -37t41 -95q0 -42 -31 -71q-22 -23 -68 -54z" id="x33"></path></g><g transform="matrix(.017,-0,0,-.017,11.996,10.862)"><path d="M535 230h-212v-233h-58v233h-213v50h213v210h58v-210h212v-50z" id="x2B"></path></g><g transform="matrix(.017,-0,0,-.017,25.748,10.862)"><path d="M456 178h-96v-72q0 -51 12.5 -62.5t72.5 -16.5v-27h-256v27q65 5 78 17t13 62v72h-260v28q182 271 300 426h40v-407h96v-47zM280 225v295h-2q-107 -148 -196 -295h198z" id="x34"></path></g>
</svg>), showing high intensity ERG expression. (d) ERG low and high intensity distribution percentages in patients with GS ≤ 7 versus &gt;7.</table>

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Figure 2

Figure 2: ERG Protein Expression Is of Limited Prognostic Value in Men with Localized Prostate Cancer 