Research Article

Role of HPV-16 in Pathogenesis of Oral Epithelial Dysplasia and Oral Squamous Cell Carcinoma and Correlation of p16INK4A Expression in HPV-16 Positive Cases: An Immunohistochemical Study

Table 2

Histopathological grading of OSCC and HPV 16 positivity.

Degree of differentiationHPV 16 positive (%)HPV 16 negative (%)

Well5 (71.44%)8 (61.14%)
Moderate1 (14.28%)4 (30.77%)
Poor1 (14.28%) 1 (7.69%)

Total7 (35%)13 (65%)

Z test, significant, .