Effects of Rituximab on the Development of Viral and Fungal Infections in Renal Transplant Recipients
Table 2
Baseline and posttransplant immunosuppression.
Variable
RTX
No RTX
value
IL2ra induction, % ()
18 (10)
40 (156)
0.001
Perioperative ATG, % ()
84 (46)
63 (242)
0.001
Perioperative IVIG, % ()
33 (18)
2 (5)
0.001
Tacrolimus at discharge, % ()
100 (55)
100 (386)
Mycophenolate at discharge, % ()
100 (55)
100 (386)
Prednisone withdrawal, % ()
5 (3)
13 (51)
0.07
Acute rejection, % ()
51 (28)
15 (56)
0.001
Antibody-mediated rejection, % ()
23 (12)
3 (11)
0.001
ATG for rejection, % ()
29 (16)
7 (28)
0.001
Total ATG exposure, (mg/kg)
0.001
Abbreviations—IL2ra: interleukin-2 receptor antagonist; ATG: antithymocyte globulin; IVIG: intravenous immune globulin.
aConcurrent viral disease includes history of hepatitis B, hepatitis C, or human Immunodeficiency virus.