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ISRN Oncology
Volume 2013 (2013), Article ID 829486, 10 pages
Research Article

Clinical Stages in Patients with Primary and Subsequent Cancers Based on the Czech Cancer Registry 1976–2005

1Department of Science and Research, University Hospital Brno, Jihlavska 20, 625 00 Brno, Czech Republic
2Laboratory on Geoinformatics and Cartography, Department of Geography, Faculty of Science, Masaryk University, Kotlarska 2, 611 37 Brno, Czech Republic
3Department of Internal Medicine, University Hospital Brno, Pekarska 53, 602 00 Brno, Czech Republic
4Department of Surgery, University Hospital Brno, Jihlavska 20, 625 00 Brno, Czech Republic

Received 13 April 2013; Accepted 9 June 2013

Academic Editors: N. Fujimoto, O. Hansen, R. Nahta, K. Sonoda, M. Stracke, and K. van Golen

Copyright © 2013 Edvard Geryk et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Of 1,486,984 new cancers registered in the Czech Cancer Registry in 1976-2005, 290,312 (19.5%) were multiple malignant neoplasms (MMNs), of which there were 65,292 primary and 89,796 subsequent cases in men and 59,970 primary and 75,254 subsequent cases in women. The duplicities were higher in women, and the triplicities and others (3–6 MMNs) were higher in men. The most frequent diagnoses were the primary cancers of skin, gastrointestinal and urinary tract, male genital organs, respiratory tract in men, and cancers of skin, breast, female genital organs, and gastrointestinal tract in women. The analysis of the early and advanced clinical stages shows that the number of subsequent advanced stages increased after primary advanced stages. Their time-age-space distributions visualized maps of MMNs in 14 Czech regions. These results support the improvement of algorithms of dispensary care for the early detection of the subsequent neoplasms.