VGLUTs in Peripheral Neurons and the Spinal Cord: Time for a Review

Table 4

Percentage of DRG neurons (visceral or nonvisceral) expressing VGLUTs and CGRP, IB4, or other VGLUTs.

Colocalization	Species	Percent nonvisceral afferents	Percent visceral afferents (target organ)
VGLUT1 also CGRP	Mouse	Not detectable [53, 54]	Not detectable (Colorectum [61], U. Bladder [62])
	Rat	Not detectable [48]	NE (Colorectum, U. bladder)
VGLUT1 also IB4	Mouse	Not detectable [53, 54]	NE (Colorectum, U. Bladder)
	Rat	NE	NE (Colorectum, U. Bladder)
VGLUT2 also CGRP	Mouse	~31% [54]	~81% (Colorectum [61])
	Rat	NE	~53% (U. Bladder [62])
VGLUT2 also IB4	Mouse	~42% [54]	NE (Colorectum, U. Bladder); NE (Colorectum, U. Bladder)
	Rat	NE	NE (Colorectum, U. Bladder)
VGLUT3 also CGRP	Mouse	Not detectable [66]	Not detectable (Colorectum*, U. Bladder [62])
	Rat	NE	NE (Colorectum, U. Bladder)
VGLUT3 also IB4	Mouse	~7% [66]	NE (Colorectum, U. Bladder)
	Rat	NE	NE (Colorectum, U. Bladder)
VGLUT2 also VGLUT1	Mouse	~14% [54]	Highly likely (Colorectum [61], U. Bladder [62])
VGLUT2 also VGLUT3	Mouse	~100%*	Highly likely (Colorectum [61], U. Bladder [62])
VGLUT1 also VGLUT3	Mouse	Not detectable*	NE (Colorectum, U. Bladder)
VGLUT2 also VGLUT1; VGLUT2 also VGLUT3; VGLUT1 also VGLUT3	Rat	NE	NE (Colorectum, U. Bladder)

NE: not evaluated; *unpublished data; tissue has been processed and NPs quantified according to references [54, 60–62].