Vasculotoxic and Proinflammatory Effects of Plasma Heme: Cell Signaling and Cytoprotective Responses
Figure 3
HO-1 expression is elevated in the organs of sickle mice. Western blots for HO-1 were performed on organ homogenates (1 μg of homogenate DNA per lane) from lungs, livers, and spleens of untreated normal mice and S + S-Antilles, and BERK sickle mice. The 32 kD HO-1 bands are shown for each organ and each mouse (a). The mean HO-1 band intensities () ± SD are expressed as fold above normal control mice (b). normal versus sickle. Figure derived from [61] American Society for Clinical Investigation.
