Table of Contents
ISRN Neurology
Volume 2013 (2013), Article ID 841902, 3 pages
http://dx.doi.org/10.1155/2013/841902
Clinical Study

Zonisamide Induces Crystalluria without Urinary pH Changes in Children and Young Adults

Kyoto Unit Center for Japan Environment & Children’s Study, Kyoto University, Graduate School of Medicine, Yoshida-Konoe-cho, Sakyo-ku, Kyoto 606-8501, Japan

Received 8 May 2013; Accepted 24 August 2013

Academic Editors: C.-M. Chen, E. A. Joosten, and A. Lewén

Copyright © 2013 Tohshin Go. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. G. Kluger, A. Zsoter, and H. Holthausen, “Long-term use of zonisamide in refractory childhood-onset epilepsy,” European Journal of Paediatric Neurology, vol. 12, no. 1, pp. 19–23, 2008. View at Publisher · View at Google Scholar · View at Scopus
  2. M. Kubota, M. Nishi-Nagase, Y. Sakakihara et al., “Zonisamide—induced urinary lithiasis in patients with intractable epilepsy,” Brain and Development, vol. 22, no. 4, pp. 230–233, 2000. View at Publisher · View at Google Scholar · View at Scopus
  3. I. E. Leppik, L. J. Willmore, R. W. Homan et al., “Efficacy and safety of zonisamide: results of a multicenter study,” Epilepsy Research, vol. 14, no. 2, pp. 165–173, 1993. View at Publisher · View at Google Scholar · View at Scopus
  4. T. Go, “Effect of antiepileptic drug monotherapy on crystalluria in children and young adults,” Journal of Neurology, vol. 250, no. 10, pp. 1251–1252, 2003. View at Publisher · View at Google Scholar · View at Scopus
  5. T. Go, “Effect of antiepileptic drug polytherapy on crystalluria,” Pediatric Neurology, vol. 32, no. 2, pp. 113–115, 2005. View at Publisher · View at Google Scholar · View at Scopus
  6. T. Go, “Effect of antiepileptic drug monotherapy on urinary pH in children and young adults,” Child's Nervous System, vol. 22, no. 1, pp. 56–59, 2006. View at Publisher · View at Google Scholar · View at Scopus
  7. T. Go, “Effect of antiepileptic drug polytherapy on urinary pH in children and young adults,” Child's Nervous System, vol. 25, no. 2, pp. 237–240, 2009. View at Publisher · View at Google Scholar · View at Scopus
  8. K. E. Paisley and C. R. V. Tomson, “Calcium phosphate stones during long-term acetazolamide treatment for epilepsy,” Postgraduate Medical Journal, vol. 75, no. 885, pp. 427–428, 1999. View at Google Scholar · View at Scopus
  9. Y. Masuda and T. Karasawa, “Inhibitory effect of zonisamide on human carbonic anhydrase in vitro,” Arzneimittel-Forschung, vol. 43, no. 4, pp. 416–417, 1993. View at Google Scholar · View at Scopus
  10. G. Zaccara, L. Tramacere, and M. Cincotta, “Drug safety evaluation of zonisamide for the treatment of epilepsy,” Expert Opinion on Drug Safety, vol. 10, no. 4, pp. 623–631, 2011. View at Publisher · View at Google Scholar · View at Scopus