|
| Excipient name (commercial name) | Examples of commercial products in which it has been used | References |
|
| Lipid ingredients |
Corn oil, mono-, di-, triglycerides,
DL-alpha-Tocopherol | Neorol oral solution,
Fortavase soft gelatin capsule | [2] |
| Mixture of mono- and diglycerides of caprylic/capric acid (Akoline) | Avodart soft gelatin capsule | [34] |
| Triglyceride of the fractionated plant fatty acids C8 und C10 (Miglyol) | Rocaltrol soft gelatin capsule,
Hectrol soft gelatin capsule | [34] |
| Capryol 90 (propylene glycol monocaprylate) | | [32, 35, 36] |
| Captex 355 (glycerol caprylate caprate) | | [35] |
| Capmul MCM L8 (glyceryl mono-dicaprylate1,2,3- propanetriol decanoic acid monoester) | | [22, 35] |
| Oleic acid/ethyl oleate | Ritonavir soft gelatin capsule,
Norvir soft gelatin capsule | [37] |
|
| Surfactants/cosurfactants |
| Polysorbate 20 (Tween 20) | Targretin soft gelatin capsule | [38] |
| Polysorbate 80 (Tween 80) | Gengraf hard gelatin capsule | [34, 35] |
| Sorbitan monooleate (Span 80) | Gengraf hard gelatin capsule | [39] |
| Polyoxy-35-castor oil (Cremophor EL) | Gengraf hard gelatin capsule,
Ritonavir soft gelatin capsule | [40] |
| Polyoxy-40-hydrogenated castor oil (Cremophor RH40) | Nerol soft gelatin capsule,
Ritonavir oral solution | [37, 41] |
| Nikkol HCO-50 (PEG 40 hydrogenated castor oil) | | [40] |
| Polyoxyethylated glycerides (Labrafil M 2125 Cs) | Sandimmune soft gelatin capsules | [36] |
| Polyoxyethylated oleic glycerides (Labrafil M 1944 Cs) | Sandimmune oral solution
| [35, 36, 42, 43] |
| Labrasol | | [36, 37] |
|
| Cosurfactants |
| Ethanol/glycerine/polypropylene glycol | Nerol, Sandimmune, Lamprene soft gelatin capsule, Nerol oral solution, Gengraf hard gelatin capsule, | |
| Polyethylene glycol | Targretin soft gelatin capsule, Gengraf hard gelatin capsule, Agenerase soft capsule, Agenerase oral solution | [22, 34, 35] |
| Transcutol | | [40] |
|
| Inert adsorbents |
| Aerosil 200 | | [36] |
| Microcrystalline cellulose | | [34] |
| Neusilin | | [44] |
| Dextran | | [43, 45] |
|
