Review Article
Formulation Strategies to Improve the Bioavailability of Poorly Absorbed Drugs with Special Emphasis on Self-Emulsifying Systems
Table 4
SEDDSs and their potential to solve various problems associated with the drug molecule.
| BCS class | Problems proposed to be solved by SEDDS |
| BCS class I | Enzymatic degradation, acidic degradation, gastric irritation, gut wall efflux | BCS class II | Solubilization, pH dependent solubilization, low bioavailability | BCS class III | Enzymatic degradation, gut wall efflux, low permeability, low bioavailability | BCS class IV | Solubilization, enzymatic degradation, gut wall efflux, low permeability, low bioavailability |
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