Formulation Strategies to Improve the Bioavailability of Poorly Absorbed Drugs with Special Emphasis on Self-Emulsifying Systems

Table 4

SEDDSs and their potential to solve various problems associated with the drug molecule.

BCS class	Problems proposed to be solved by SEDDS
BCS class I	Enzymatic degradation, acidic degradation, gastric irritation, gut wall efflux
BCS class II	Solubilization, pH dependent solubilization, low bioavailability
BCS class III	Enzymatic degradation, gut wall efflux, low permeability, low bioavailability
BCS class IV	Solubilization, enzymatic degradation, gut wall efflux, low permeability, low bioavailability