Some Haematological and Biochemical Investigations on Duck Virus Hepatitis following Administration of Glycyrrhizin

Table 5

Serum enzymes, creatinine, and uric acid of different experimental groups of ducklings before (at the 1st, 2nd, and 3rd weeks) and after challenge (at the 4th week) (mean ± standard deviation).

		Groups
Parameters	Periods (weeks)	Control (1)		(2)	(3)	(4)	LSD
		Normal	After challenge	Glycyrrhizin	DHV vaccine	Glycyrrhizin + DHV vaccine
Aspartate aminotransferase (IU/L)	1	188.47±7.36		177.00±13.61	228.47^∗±1.08	194.00±0.00	10.39
	2	186.86±2.28		186.93±3.58	195.48^∗±1.48	181.56±9.80	7.23
	3	153.71±5.88		140.56±5.87	146.17±17.92	142.20±6.06	13.85
	4^#	174.59^b±3.42	350.07^∗±13.33	179.95^b±10.72	261.20^∗b±17.78	228.13^∗b±2.84	14.82
Alanine aminotransferase (IU/L)	1	180.44±27.03		189.10±7.80	252.38^∗±27.77	186.36±4.36	26.66
	2	184.65±5.08		171.88±0.06	198.11±17.80	184.82±1.28	12.44
	3	181.66±18.23		149.73±12.70	186.75±4.85	176.37±27.32	23.83
	4^#	182.48^b±4.23	290.84^∗±27.35	192.84^b±9.83	235.60^∗b±14.42	210.52^∗b±12.88	20.78
Alkaline phosphate (IU/L)	1	166.97±15.58		161.01±10.18	264.98^∗±18.78	90.67^∗±14.55	0.24
	2	152.33±3.11		147.80±10.97	166.05^∗±9.08	127.93±12.65	12.94
	3	153.35±5.36		146.02±4.78	162.94^∗±5.23	139.52±8.33	8.16
	4^#	156.39^b±3.93	251.59^∗±24.47	171.66^b±7.89	202.00^∗b±16.67	211.23^∗b±23.61	22.99
Creatinine (mg/dL)	1	1.68±0.02		1.74±0.04	2.24^∗±0.05	2.08±0.01	0.47
	2	1.02±0.02		1.22±0.03	2.54^∗±0.03	1.33±0.18	0.36
	3	1.41±0.04		1.39±0.04	1.83±0.10	1.78±0.04	0.47
	4^#	1.59^b±0.04	4.30^∗±0.64	1.94^b±0.32	3.55^∗b±0.27	2.08^∗b±0.39	0.59
Uric acid (mg/dL)	1	2.68±0.48		4.23±0.33	6.25^∗±1.87	3.99±0.33	1.59
	2	4.78±0.15		3.00±0.13	4.01±0.17	2.96±0.09	2.04
	3	3.04±0.40		2.61±0.21	3.64±0.10	3.95±0.4	1.32
	4^#	7.93^b±1.79	21.54^∗±1.54	6.01^𝐛±1.55	21.26^∗±1.32	16.68^∗±3.17	9.76

4^# After challenge (at the 4th week).
∗Significant compared to control normal group in the same row.
bSignificant compared to control-infected group at the 4th week.
DHV: duck hepatitis virus.
LSD: least significant difference.