Role of Candidate Genes Regulating Uterine Prostaglandins Biosynthesis for Maternal Recognition of Pregnancy in Domestic Animals

<table>Selective representation for production of PGE2 and PGF2<i>α</i>. Steps involved (i) release of arachidonic acid (AA) from plasma membrane phospholipids through cytosolic phospholipase A2 (cPLA2). (ii) Conversion of AA into PGH2, the common precursor for all PGs, occurs through PGH synthase/COX, for which there are two isoforms COX-1 and COX-2. (iii)  Conversion of PGH2 into  active PG by terminal synthase PGES and PGFS.</table>

International Scholarly Research Notices

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Figure 1

Figure 1: Role of Candidate Genes Regulating Uterine Prostaglandins Biosynthesis for Maternal Recognition of Pregnancy in Domestic Animals 