Spectrophotometric Determination of Bromhexine HCl in Pure and Pharmaceutical Forms

Table 3

Application of proposed methods for the determination of BRH in pharmaceutical preparation.

BRH	BTB (A)	BPB (B)	BCG ( C)	I2 (D)	KMnO4 (E)
Taken (µg mL^−1)	5.00	5.00	5.00	10.00	20.00
	7.00	7.00	7.00	20.00	30.00
	9.00	9.00	9.00	30.00	40.00
	11.00	11.00	11.00	40.00	50.00
Found (µg mL^−1)	4.95	5.04	4.98	9.96	20.06
	6.94	6.97	7.06	19.94	29.95
	9.05	8.97	9.05	29.96	40.03
	10.94	11.07	11.08	40.02	50.09
Recovery (%)	101.01	99.21	100.40	100.40	99.70
	100.86	100.43	99.15	100.30	100.17
	99.45	100.33	99.45	100.13	99.93
	100.55	99.37	99.28	99.95	99.82
Mean	100.47	99.83	99.57	100.20	99.90
SD	1.12	1.55	2.20	0.97	1.70
Reference method [14]	99.77±0.48	99.77±0.48	99.77±0.48	99.77±0.48	99.77±0.48
𝑡-test (1.10)*	1.28	0.08	0.19	0.88	0.16
𝐹-test (2.61)*	1.25	2.40	4.84	0.94	2.89

Each result is the average of four separate determinations. ∗Values in paranthesis are the tabulated 𝑡 and 𝐹 values, at 𝑃=0.05 [27].