Model of Neocortex. The detailed model (after [6]) is outlined in diagram (a). The excitatory populations consist of superficial (S_PYR) and deep (D_PYR) pyramidal cells and the inhibitory neuron type (I) consists of populations of basket cells (B) and chandelier cells (CH). The weighted sum of all soma currents is used as the “EEG” signal (top, (a)). The excitatory connections of the microcircuitry are shown in the left part, and the inhibitory synapses in the right part of (a). (b) depicts a detail of the EEG during seizure-like oscillation in the “EEG” and the associated raster plots of the S_PYR and D_PYR populations. The simplified network version, after Visser et al. [65], where only excitatory pyramidal cells and inhibitory neuronal populations are considered, is shown in the right part of (b). (c) The average membrane potentials of both pyramidal cell populations show that the activities of the deep S_PYR and D_PYR populations alternate during seizure-like oscillation.
