Table of Contents
ISRN Radiology
Volume 2013, Article ID 874570, 8 pages
Research Article

Automated Determination of Bone Age in a Modern Chinese Population

1Hebei Research Institute of Sports Sciences, 372 Zhongshan East Road, Shijiazhuang, Hebei 050011, China
2Dalian Sports Science Research Institute, 31 Shikui Road, Dalian, Liaoning 116011, China
3Wenzhou Sports Science Research Institute, 22 Youyongqiao Road, Wenzhou, Zhejiang 325000, China
4Shanghai Sports Sciences Research Institute, 87 Wuxing Road, Shanghai 200030, China
5Guangdong Sports Science Research Institute, 818 Aoti Road, Guangzhou, Guangdong 510663, China
6Visiana, Søllerødvej 57 C, 2840 Holte, Denmark

Received 30 November 2012; Accepted 20 December 2012

Academic Editors: G. Borasi and S. Mori

Copyright © 2013 Shao-Yan Zhang et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Rationale and Objective. Large studies have previously been performed to set up a Chinese bone age reference, but it has been difficult to compare the maturation of Chinese children with populations elsewhere due to the potential variability between raters in different parts of the world. We re-analysed the radiographs from a large study of normal Chinese children using an automated bone age rating method to establish a Chinese bone age reference, and to compare the tempo of maturation in the Chinese with other populations. Materials and Methods. X-rays from 2883 boys and 3143 girls aged 2–20 years from five Chinese cities, taken in 2005, were evaluated using the BoneXpert automated method. Results. Chinese children reached full maturity at the same age as previously studied Asian children from Los Angeles, but 0.6 years earlier than Caucasian children in Los Angeles. The Greulich-Pyle bone age method was adapted to the Chinese population creating a new bone age scale BX-China05. The standard deviation between BX-China05 and chronologic age was 1.01 years in boys aged 8–14, and 1.08 years in girls aged 7–12. Conclusion. By eliminating rater variability, the automated method provides a reliable and efficient standard for bone age determination in China.