Table of Contents
ISRN Epidemiology
Volume 2013 (2013), Article ID 876724, 6 pages
http://dx.doi.org/10.5402/2013/876724
Research Article

Maternal Age at First Delivery and Risk of Cardiovascular Disease Later in Life

1School of Health Sciences, University of Tampere, 33014 Tampere, Finland
2UKK Institute for Health Promotion, 33501 Tampere, Finland
3Department of Children and Families, National Health and Welfare Institute, 00271 Helsinki, Finland

Received 13 January 2013; Accepted 9 February 2013

Academic Editors: H. B. Bueno-de-Mesquita, M. Lancellotti, and A. Singanayagam

Copyright © 2013 Elham Kharazmi et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background. To elucidate the association between maternal age at first delivery and cardiovascular health in women. Material and Method. A nationally representative survey, comprising 3,937 Finnish women aged 30–99 years with information on most of the potential cardiovascular disease (CVD) risk factors. Weighting survey analyses and logistic regression were performed. Results. Women who had their first delivery at age 25 or less had about five times higher odds ratio for myocardial infarction (fully adjusted OR: 4.82; 95% CI: 1.39–16.75) and about 2-fold higher odds ratio of arrhythmia (fully adjusted OR: 1.82; 95% CI: 1.13–2.92) compared to those who were 31–35 years at their first delivery. Each one year younger maternal age at first delivery predicted a higher risk of myocardial infarction (age-adjusted ; 95% CI: 1.06–1.18), hypertension (age-adjusted ; 95% CI: 1.03–1.07), arrhythmia (age-adjusted OR = 1.03; 95% CI: 1.01–1.05), angina pectoris (age-adjusted OR = 1.06; 95% CI: 1.02–1.10), and heart failure (age-adjusted ; 95% CI: 1.01–1.10). Conclusion. Maternal earlier age at first delivery is related to subsequent development of CVD, especially myocardial infarction. Our findings suggest a need for additional care and monitoring for CVD and its risk factors in women who had their first delivery at young ages.