The Human Frontal Lobes and Frontal Network Systems: An Evolutionary, Clinical, and Treatment Perspective

Table 9

Junque Leukoaraiosis grading [26].

Evaluate 5 areas in each hemisphere
(i) Centrum semiovale in frontal region
(ii) Centrum semiovale parietal region
(iii) White matter surrounding frontal horn
(iv) White matter surrounding corpus of the lateral ventricle
(v) White matter surrounding the atrium and occipital horn of lateral ventricle
Numerical scores 1–4 of T2 hyperintensity
(i) No changes	0
(ii) <25%	1
(iii) 25%–50%	2
(iv) 50%–75%	3
(v) >75%	4
Total score	0–40