Lesion-Induced Alterations in Astrocyte Glutamate Transporter Expression and Function in the Hippocampus
Figure 4
Lesion-induced changes in somatic area. (a) Quantification of somatic area based on GFAP/GFP fluorescence in control and lesioned slices. The soma size increased both in astrocytes in the scar region (“scar”) and in astrocytes in the periphery of the lesion (“periphery”; ***; *). (b) Confocal images of GFP fluorescence in cultured slices obtained from GFP/GFAP transgenic animals under control conditions (left) and subjected to a lesion (right). Cells surrounded by boxes are shown at higher magnification in the insets, and the dashed lines around the soma illustrate the areas which served to determine their size. StrP, stratum pyramidale; StrR, stratum radiatum; StrLM, stratum lacunosum moleculare; and scale bars: 40 μm and 10 μm (inset).
