Review Article
The Mortality in Emergency Department Sepsis Score as a Predictor of 1-Month Mortality among Adult Patients with Sepsis: Weighing the Evidence
Table 2
Summary of included studies.
| | Hermans et al., 2012 [23] | Lee et al., 2008 [24] | Vorwerk et al., 2009 [26] | Zhao et al., 2013 [25] |
| Study design | Retrospective cohort study | Prospective cohort study | Retrospective cohort study | Prospective cohort study |
|
Study population | (i) One centre (tertiary) (ii) Adult ED patients (>18 years old) | (i) One centre (tertiary) (ii) Adult ED patients (≥15 years old) | (i) Two centres (one urban teaching and one district general) (ii) Adult ED patients (>16 years old) | (i) One centre (tertiary) (ii) Adult ED patients (>18 patients) | Sample size of 331 patients (i) Sepsis (62%) (ii) Severe sepsis (30%) (iii) Septic shock (4%) | Sample size of 525 patients (i) Sepsis (76%) (ii) Severe sepsis (19%) (iii) Septic shock (5%) | Sample size of 307 patients (i) No further information about categorisation by severity of sepsis | Sample size of 501 patients (i) Sepsis (64%) (ii) Severe sepsis (31%) (iii) Septic shock (5%) |
| Prognostic determinant | MEDS score | MEDS score | Abbreviated MEDS score | MEDS score |
| Comparator | C-reactive protein | C-reactive protein | — | C-reactive protein | — | Procalcitonin | — | Procalcitonin | Lactate | — | Lactate | — | — | — | — | Interleukin-6 | — | — | — | MEDS + procalcitonin |
| Outcome | 28-day mortality | 5-day (early) and 6- to 30-day (late) mortality | 28-day mortality | 28-day mortality |
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ED: emergency department; MEDS score: Mortality in Emergency Department Sepsis score.
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