No Association between Depression and Risk of Hepatocellular Carcinoma in Older People in Taiwan

Table 2

Odds ratio and 95% confidence interval of hepatocellular carcinoma associated with depression and other comorbidities.

Variable	Crude		Adjusted^†
	OR	(95% CI)	OR	(95% CI)
Age (per one year)	1.01	(1.00, 1.01)	1.04	(1.03, 1.05)
Comorbidities before index date (yes versus no)
Depression	1.20	(0.97, 1.49)	0.81	(0.59, 1.11)
Diabetes mellitus	1.48	(1.33, 1.65)	1.04	(0.89, 1.22)
Cirrhosis	62.39	(51.46, 75.65)	28.55	(23.17, 35.19)
Other chronic hepatitis	6.93	(6.19, 7.75)	2.23	(1.89, 2.63)
Hepatitis B infection	15.84	(12.72, 19.73)	5.87	(4.40, 7.84)
Hepatitis C infection	26.06	(21.42, 31.72)	7.72	(6.00, 9.93)
Alcoholism	1.70	(1.05, 2.74)	0.85	(0.43, 1.68)

†Adjusted for age, diabetes mellitus, cirrhosis, other chronic hepatitis, hepatitis B infection, hepatitis C infection, and alcoholism.