Reference Analysis in a Misclassification Model for the Meiosis I Nondisjunction Fraction in Trisomies

<table>Jeffreys prior distribution for <svg height="16.625" id="M128" style="vertical-align:-3.56265pt" version="1.1" viewbox="0 0 39.3125 16.625" width="39.3125" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,12.138)"><path d="M300 -147l-18 -23q-106 71 -159 185.5t-53 254.5v1q0 139 53 252.5t159 186.5l18 -24q-74 -62 -115.5 -173.5t-41.5 -242.5q0 -130 41.5 -242.5t115.5 -174.5z" id="x28"></path></g><g transform="matrix(.017,-0,0,-.017,5.944,12.138)"><path d="M542 242q0 -106 -80 -176.5t-192 -72.5l-55 -251l-6 -3q-18 7 -28 38t1 91l23 124q-85 16 -133.5 72.5t-48.5 137.5q0 95 62.5 159.5t166.5 97.5l14 -31q-77 -32 -115 -82.5t-38 -128.5q0 -63 31.5 -107t74.5 -59l125 597l56 43l16 -10l-40 -168q-9 -40 3 -45
q77 -33 120 -85.5t43 -140.5zM469 232q0 67 -37 115t-77 62l-76 -370q89 -4 139.5 52.5t50.5 140.5z" id="x1D719"></path></g><g transform="matrix(.017,-0,0,-.017,15.548,12.138)"><path d="M95 130q31 0 61 -30t30 -78q0 -53 -38 -87.5t-93 -51.5l-11 29q77 31 77 85q0 26 -17.5 43t-44.5 24q-4 0 -8.5 6.5t-4.5 17.5q0 18 15 30t34 12z" id="x2C"></path></g><g transform="matrix(.017,-0,0,-.017,22.246,12.138)"><path d="M642 419q-50 -36 -71 -94q-28 -78 -68 -170q-39 -89 -114 -135q-34 -21 -83 -31l-45 -219l-31 -31q-8 7 -15 29.5t-2 45.5l35 172q-153 10 -153 169q0 28 6 84q7 68 7 88q0 48 -27 48q-18 0 -51 -28l-7 26q62 75 118 75q49 0 49 -90q0 -47 -5 -81q-10 -72 -10 -108
q0 -117 82 -133l87 455l62 19l7 -2l-99 -478q91 12 131 120q34 93 51 154q20 73 36 88q42 40 103 56z" id="x1D713"></path></g><g transform="matrix(.017,-0,0,-.017,33.363,12.138)"><path d="M275 270q0 -296 -211 -440l-19 23q75 62 116.5 174t41.5 243t-42 243t-116 173l19 24q211 -144 211 -440z" id="x29"></path></g>
</svg>.</table>

International Scholarly Research Notices

fig3

Figure 3

Figure 3: Reference Analysis in a Misclassification Model for the Meiosis I Nondisjunction Fraction in Trisomies 