Table of Contents
ISRN Dermatology
Volume 2013 (2013), Article ID 907189, 4 pages
http://dx.doi.org/10.1155/2013/907189
Research Article

Effect of Infliximab on the UVB-Induced Apoptosis of Keratinocytes Infected by HPV38 E6/E7

1Molecular and Cell Biology Laboratory, Université de Franche Comté, EA3181, SFR FED4234, Besançon, France
2Department of Dermatology, Centre Hospitalier Universitaire, 25030 Besançon, France
3Department of Infections and Cancer Biology, IARC, Lyon, France

Received 7 January 2013; Accepted 26 January 2013

Academic Editors: M. Alaibac, S.-C. Chao, E. Pasmatzi, Y. Tuzun, and J. F. Val Bernal

Copyright © 2013 François Aubin et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. E. Boccardo, C. V. M. Baldi, A. F. Carvalho et al., “Expression of human papillomavirus type 16 E7 oncoprotein alters keratinocytes expression profile in response to tumor necrosis factor-α,” Carcinogenesis, vol. 31, no. 3, pp. 521–531, 2010. View at Publisher · View at Google Scholar · View at Scopus
  2. J. Askling, K. Fahrbach, B. Nordstrom, S. Ross, C. H. Schmid, and D. Symmons, “Cancer risk with tumor necrosis factor alpha (TNF) inhibitors: meta-analysis of randomized controlled trials of adalimumab, etanercept, and infliximab using patient level data,” Pharmacoepidemiology and Drug Safety, vol. 20, no. 2, pp. 119–130, 2011. View at Publisher · View at Google Scholar · View at Scopus
  3. M. R. Iannacone, T. Gheit, T. Waterboer et al., “Case-control study of cutaneous human papillomaviruses in squamous cell carcinomas of the skin,” Cancer Epidemiology, Biomarkers & Prevention, vol. 21, no. 8, pp. 1303–1313, 2012. View at Google Scholar
  4. R. Accardi, W. Dong, A. Smet et al., “Skin human papillomavirus type 38 alters p53 functions by accumulation of ΔNp73,” EMBO Reports, vol. 7, no. 3, pp. 334–340, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. S. Caldeira, I. Zehbe, R. Accardi et al., “The E6 and E7 proteins of the cutaneous human papillomavirus type 38 display transforming properties,” Journal of Virology, vol. 77, no. 3, pp. 2195–2206, 2003. View at Publisher · View at Google Scholar · View at Scopus
  6. S. Domm, J. Cinatl, and U. Mrowietz, “The impact of treatment with tumour necrosis factor-α antagonists on the course of chronic viral infections: a review of the literature,” British Journal of Dermatology, vol. 159, no. 6, pp. 1217–1228, 2008. View at Publisher · View at Google Scholar · View at Scopus
  7. J. S. Guerrini, V. Bouvard, E. Oswald et al., “E6 and E7 proteins from different beta-papillomaviruses types do not interfere in UVB-induced apoptosis of HaCaT keratinocytes,” Experimental Dermatology, vol. 20, no. 1, pp. 71–73, 2011. View at Publisher · View at Google Scholar
  8. A. Köck, T. Schwarz, R. Kirnbauer et al., “Human keratinocytes are a source for tumor necrosis factor α: evidence for synthesis and release upon stimulation with endotoxin or ultraviolet light,” Journal of Experimental Medicine, vol. 172, no. 6, pp. 1609–1614, 1990. View at Publisher · View at Google Scholar · View at Scopus
  9. A. Faurschou, R. Gniadecki, D. Calay, and H. C. Wulf, “TNF-α impairs the S-G2/M cell cycle checkpoint and cyclobutane pyrimidine dimer repair in premalignant skin cells: role of the PI3K-Akt pathway,” Journal of Investigative Dermatology, vol. 128, no. 8, pp. 2069–2077, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. A. Schwarz, R. Bhardwaj, Y. Aragane et al., “Ultraviolet-B-induced apoptosis of keratinocytes: evidence for partial involvement of tumor necrosis factor-α in the formation of sunburn cells,” Journal of Investigative Dermatology, vol. 104, no. 6, pp. 922–927, 1995. View at Google Scholar · View at Scopus
  11. I. Hussain, I. Fathallah, R. Accardi et al., “NF-kappaB protects human papillomavirus type 38 E6/E7-immortalized human keratinocytes against tumor necrosis factor alpha and UV-mediated apoptosis,” Journal of Virology, vol. 85, no. 17, pp. 9013–9022, 2011. View at Publisher · View at Google Scholar
  12. T. Gambichler, C. Tigges, A. Dith et al., “Impact of etanercept treatment on ultraviolet B-induced inflammation, cell cycle regulation and DNA damage,” British Journal of Dermatology, vol. 164, no. 1, pp. 110–115, 2011. View at Publisher · View at Google Scholar · View at Scopus
  13. A. Faurschou, R. Gniadecki, and H. C. Wulf, “Infliximab inhibits DNA repair in ultraviolet B-irradiated premalignant keratinocytes,” Experimental Dermatology, vol. 17, no. 11, pp. 933–938, 2008. View at Publisher · View at Google Scholar · View at Scopus