Research Article

Effect of Physical Exercise on the Level of DNA Damage in Chronic Obstructive Pulmonary Disease Patients

Table 3

DNA damage and TBARS in the COPD and PE-COPD by status diseases.

Disease statusDamage index-comet assay
GroupNeutralAlkalineFPGENDO IIIResidual damage TBARSa

Mild and moderatedCOPD ( ) 160.53 ± 90.23
PE-COPD ( ) 94.71 ± 26.76
value0.0240.0280.022NSNS0.007

SevereCOPD ( ) 160.25 ± 70.36
PE-COPD ( ) 120.75 ± 86.06
valueNSNS0.0040.049NS0.031

Very severeCOPD ( ) 196.00 ± 68.02
PE-COPD ( ) 104.75 ± 38.42
valueNSNS0.027NSNSNS

Data are presented as mean ± SD; anmol/mg of protein; : sample numbers; NS: not significant.