International Scholarly Research Notices / 2013 / Article / Tab 4

Research Article

Effect of Physical Exercise on the Level of DNA Damage in Chronic Obstructive Pulmonary Disease Patients

Table 4

Correlations between the parameters analyzed in patients and controls.

Parameters
COPDPE-COPD
Spearman’s rho valueSpearman’s rho value

FEV1/FVC—BUD−0.3850.027−0.3850.210
FEV1/FVC—KR−0.3990.021−0.6110.016
FEV1—KR−0.2770.119 0.527 0.043
Basal DI in neutral comet assay—BUD 0.360 0.039 0.524 0.045
DI following 3 h MMS treatment—KL−0.5510.001 0.172 0.539
% Residual damage—KR 0.528 0.002 0.183 0.514

FEV1/FVC: ratio of forced expiratory volume in one second to forced vital capacity; BUD: nuclear buds; KR: karyorrhectic cells; KL: karyolytic cells; DI: damage index; MMS: methyl methanesulphonate; % residual damage, calculated for DI after 3 h MMS treatment for each subject taking the value of DI after 1 h MMS treatment as 100%.