International Scholarly Research Notices

Research Article

Effect of Physical Exercise on the Level of DNA Damage in Chronic Obstructive Pulmonary Disease Patients

Table 4

Correlations between the parameters analyzed in patients and controls.


Parameters	COPD		PE-COPD
Parameters	Spearman’s rho	value	Spearman’s rho	value

FEV₁/FVC—BUD	−0.385	0.027	−0.385	0.210
FEV₁/FVC—KR	−0.399	0.021	−0.611	0.016
FEV₁—KR	−0.277	0.119	0.527	0.043
Basal DI in neutral comet assay—BUD	0.360	0.039	0.524	0.045
DI following 3 h MMS treatment—KL	−0.551	0.001	0.172	0.539
% Residual damage—KR	0.528	0.002	0.183	0.514

FEV₁/FVC: ratio of forced expiratory volume in one second to forced vital capacity; BUD: nuclear buds; KR: karyorrhectic cells; KL: karyolytic cells; DI: damage index; MMS: methyl methanesulphonate; % residual damage, calculated for DI after 3 h MMS treatment for each subject taking the value of DI after 1 h MMS treatment as 100%.