Research Article
Development and Validation of a Stability Indicating RP-UPLC Method for Analysis of Imipramine Hydrochloride in Pharmaceuticals
Table 7
Method ruggedness.
| | Variable | Mean peak area ± SD* | % RSD | Mean Rt ± SD | % RSD | Mean theoretical plates ± SD* | % RSD | Mean tailing factor ± SD | % RSD |
| | Analyte () | 147474 ± 151.74 | 0.103 | 2.128 ± 0.006 | 0.28 | 2938 ± 73 | 2.48 | 1.13 ± 0.004 | 0.311 | | Column () | 147547 ± 195.53 | 0.133 | 2.129 ± 0.006 | 0.30 | 2875 ± 81 | 2.81 | 1.15 ± 0.008 | 0.73 |
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*Mean value of three determinations.
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