Clinical Study

Factors Predicting Total Free Flap Loss after Microsurgical Reconstruction Following the Radical Ablation of Head and Neck Cancers

Table 2

Characteristics of patients who developed total free flap failure.

SexAgeOriginal diseasePrimary surgeryPresurgical radiation (Gy)Presurgical chemotherapySalvage surgery

1F68Hypopharyngeal cancer (SCC )
pT2N1M0
Partial hypopharyngectomy
Neck resection Free forearm flap transfer
100TXT 360 mgFree jejunum flap transfer 
2M76Recurrent laryngeal cancer (SCC)
pT4N2M0
Partial oral base resection,
Neck resection
Free RAMC flap transfer
65PMMC flap
3F68Recurrent hypopharyngeal cancer (SCC)
pT2N1M0
Hypopharyngectomy
Neck resection
Free jejunum flap transfer
66TXT 360 mgFree jejunum flap transfer
4M57Nesopharyngeal cancer (SCC)
pT3N2bM0
TPLE,
Neck resection Free ALT flap transfer
65CDDP 100 mg, 5Fu 500 mgPMMC flap
5F26Maxillary sarcoma pT3N2bM0Radical maxillary resection,
Free scapular and LD MC flap transfer
65CDDP 500 mg, TXT 300 mgFree ALT flap
6F50Olfactory neuroblastoma pT3N2bM0Radical maxillary and skull base resection,
Orbitotomy Free RAMC flap transfer
Free ALT flap

SCC: squamous cell carcinoma. LD MC flap: latissimus dorsi musclocutaneous flap. PMMC flap: pectoralis major musclocutaneous flap.
TLPE: total laryngopharyngoesophagectomy. NR: neck resection. RAMC flap: rectus abdominal musclocutaneous flap. ALT flap: anterolateral thigh flap. CDDP: Cisplatin. TXT: docetaxel.