Impact of Eighteen-Year Varied Compliance to Onchocerciasis Treatment with Ivermectin in Sentinel Savannah Agrarian Communities in Kaduna State of Nigeria

Table 5

Changes in skin microfilaria and clinical signs.

S/No.	Parameter	Post-control data; (observed, 𝑛=592)	Baseline data; (expected, 𝑛=531)	Impact of treatment; (%)	Statistics test
(1)	Skin mf prevalence	0	144 (27.0%)	−100	t-test of unpaired data 𝑃<0.01
(2)	Nodule positive	4 (0.7%)	77 (14.4%)	−95.1	-do-
(3)	Pruritus (scratch marks)	22 (3.7%)	24 (4.5%)	−17.8	𝑃>0.05
(4)	Skin clinical manifestations	2 (0.4%)	51 (9.1%)	−96.2	-do-
(6)	Optic nerve disease	4 (0.7%)	24 (4.5%)	−77.8	𝑃<0.05
(7)	Inducible eye lesions	12 (2.0%)	31 (5.8%)	−65.5%	𝑃<0.05
(8)	Blindness (no perception of light)	6	6	0	Unchanged, no new case detected