Individuals Diagnosed with Schizophrenia Assign Emotional Importance to Neutral Stimuli: An fMRI Study
Table 3
Brain regions activated in healthy and schizophrenia men and women.
Group
L/R
Brain region
BA
MNI coordinates
-score
Voxels
value
Neutral minus rest
HM minus SCZ-M
No significant voxels activated
SCZ-M minus HM
R
Middle cingulate gyrus
31
4
−24
46
3.52
1014
0.001
L
Superior frontal gyrus
6
−18
−10
74
2.92
*
0.002
L
Inferior parietal gyrus
40
−35
−46
52
3.00
*
0.001
R
Inferior parietal gyrus
40
35
−42
52
3.05
*
0.001
L
Supplementary motor area
6
0
−4
63
3.15
*
0.001
L
Precuneus
7
−10
−56
52
3.15
*
0.001
R
Anterior cingulate gyrus
32
10
24
21
2.72
6
0.003
L
Cerebellum
—
−14
−84
−35
3.26
179
0.001
R
Cerebellum
—
10
−80
−42
2.75
8
0.003
R
Precentral gyrus
6
49
0
49
3.00
22
0.001
R
Middle frontal gyrus
10
42
46
4
2.98
94
0.001
R
Superior OFC
11
18
42
−14
2.92
15
0.002
L
Middle temporal gyrus
21
−60
−49
0
2.89
9
0.002
L
Supramarginal gyrus
40
−56
−46
28
2.81
13
0.002
HW minus SZC-W
L
Inferior occipital gyrus
19
−42
−74
−14
2.77
9
0.003
L
Calcarine gyrus
17
−4
−80
10
2.66
5
0.004
SCZ-W minus HW
R
Putamen
—
21
7
−4
3.00
25
0.001
L
Putamen
—
−18
7
0
2.76
6
0.003
R
Angular gyrus
40
56
−56
28
2.79
7
0.003
BA: Brodmann area, HM: healthy men, HW: healthy women, SCZ-M: schizophrenia men, SCZ-W: schizophrenia women, OFC: orbitofrontal cortex; *brain region part of the same cluster as above.
