Table of Contents
ISRN Tropical Medicine
Volume 2013, Article ID 987683, 7 pages
Clinical Study

Pain and Its Consequences in Quality of Life: A Study with WHOQOL-Bref in Leprosy Patients with Neuropathic Pain

1Faculdade de Medicina, Universidade Federal do Rio de Janeiro (UFRJ), Programa de Pós-Graduação em Clínica Médica, Rio de Janeiro, Brazil
2Instituto Federal do Rio de Janeiro, Campus Realengo Rua Carlos Wenceslau, 343 Realengo, 21715-000 Rio de Janeiro, RJ, Brazil

Received 5 March 2013; Accepted 9 April 2013

Academic Editors: R. Dey, V. G. Duschak, and S. Munga

Copyright © 2013 Felipe J. J. Reis et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


Chronic neuropathic pain emerges as a challenge in the treatment of leprosy patients after multidrug therapy discharge. The aim of this study was to determine the quality of life and its repercussions in leprosy patients with chronic pain. We studied male and female patients with chronic neuropathic pain in the last year. Neuropathic pain was confirmed using Douleur Neuropathique en 4 (DN4) and its intensity evaluated by visual analogue scale (VAS). A general questionnaire was applied to evaluate quality of life (WHOQOL-bref). Statistical analyses were composed by descriptive and central tendency. Spearman correlation was used to identify the relation between pain intensity, quality of life domains, and facets. Multiple linear regressions were performed to verify the influence of pain intensity on each facet. Neuropathic pain patients scored worst in physical and environment domains. The low facets were related to pain and discomfort, thinking and concentration, sexual activity, and recreation opportunities. Pain intensity has a high negative influence on psychological domain and recreation opportunities. These findings should contribute to the development of rehabilitation programs considering patients needs to improve their quality of life and true social reintegration.