An Immunological Approach to Increase the Brain’s Resilience to Insults

Figure 3

Seizure-induced damage in the hippocampus following systemic KA administration. TUNEL labeling (arrows) of neuronal cell death in the CA1 region of the hippocampus indicates the extent of damage in representative brain sections of NR1 vaccinated and control rats four days after receiving systemic kainic acid. Each image was from a different animal with the ID given in the bottom left corner. The vaccination treatment each rat had is given on the left. Scale bar = 200 μm.