Clinical Study
Treatment Planning Methods in High Dose Rate Interstitial Brachytherapy of Carcinoma Cervix: A Dosimetric and Radiobiological Analysis
Table 1
Dosimetrical and radiobiological data for the ISBT planning methods.
| | Quality metric | Gr_O (mean) | DP_N (mean/) | DP_O (mean/) | G_N (mean/) | G_O (mean/) |
| | CI | 0.7320 | 0.7360 (0.87) | 0.8561 (0.0001) | 0.8356 (0.0004) | 0.8879 (0.0001) | | EI | 0.0009 | 0.0174 (0.0001) | 0.0114 (0.0035) | 0.0441 (0.0001) | 0.0406 (0.0001) | | DHI | 0.6629 | 0.6282 (0.1647) | 0.6070 (0.049) | 0.4494 (0.0001) | 0.4764 (0.0001) | | ODI | 0.1343 | 0.1284 (0.5555) | 0.1599 (0.0077) | 0.1835 (0.0002) | 0.1514 (0.0632) | | DNR | 0.3370 | 0.3717 (0.1647) | 0.3929 (0.0049) | 0.5205 (0.0001) | 0.5535 (0.0001) | | Bl2cc | 425.65 | 461.72 (0.0697) | 473.35 (0.0078) | 524.37 (0.0001) | 533.07 (0.0001) | | R2cc | 416.12 | 520.62 (0.0001) | 504.95 (0.0001) | 595.32 (0.0001) | 620.47 (0.0001) | | TCP | 0.9952 | 0.9951 (0.0343) | 0.9958 (0.5353) | 0.9964 (0.0641) | 0.9959 (0.9274) | | NTCP-B | 0.3252 | 0.3607 (0.0001) | 0.7752 (0.0001) | 0.7115 (0.0001) | 0.8895 (0.0001) | | NTCP-R | 0.3126 | 0.7216 (0.0001) | 0.7032 (0.0001) | 0.8569 (0.0001) | 0.8112 (0.0001) |
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CI: Conformity Index; EI: External Volume Index; DHI: Dose Homogeneity Index; ODI: Overdose Volume Index; DNR: Dose nonuniformity Ratio; Bl2cc: dose to 2cc bladder volume; R2cc: dose to 2cc rectal volume; NTCP-B: normal tissue complication probability of bladder; NTCP-R: normal tissue complication probability of rectum; DP_N: volume normalization; DP_O: dose point optimization; G_N: geometrical normalization; and G_O: geometrical optimization.
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