The Presence of Mutations in the K-RAS Gene Does Not Affect Survival after Resection of Pulmonary Metastases from Colorectal Cancer

Table 4

Association between K-RAS mutation status and the other variables studied.

Variable	Native K-RAS (49 patients)	Mutated K-RAS (30 patients)	P
Origin
Rectum	32 (65.3%)	16 (53.3%)	0.290
Age
>65 years	31 (63.3%)	16 (53.3%)	0.383
Comorbidity
Present	25 (51.0%)	20 (66.7%)	0.173
CEA
Positive	12 (24.5%)	12 (40.0%)	0.245
Previous liver metastasis
Yes	8 (16.3%)	5 (16.7%)	0.968
Disease-free survival
>12 months	43 (87.8%)	25 (83.3%)	0.582
Access
VATS	4 (6.6%)^a	1 (2.7%)^b	0.392
Lymph node involvement
Yes	7 (11.7%)^a	6 (16.2%)^b	0.688
Size
>1 cm	55 (90.2%)^a	33 (89.2%)^b	0.528
Number of metastases
>1	11 (18.0%)^a	8 (21.6%)^b	0.520
Laterality
Right	37 (60.6%)^a	23 (62.2%)^b	0.626
Resection
Atypical	35 (57.4%)^a	15 (40.5%)^b	0.622

aOf 61 interventions; ^bof 37 interventions; CEA: carcinoembryonic antigen; VATS: video-assisted thoracic surgery.