Research Article

Association of Mammographic Breast Density with Dairy Product Consumption, Sun Exposure, and Daily Activity

Table 2

Studies about association of MD with dairy product intake, sunlight exposure, or physical activity.

AuthorsStudied factor Pub yr*Study design and detailsType of association

Bérubé et al. [31]Calcium containing foods**2004(i) Semiquantitative food frequency questionnaire
(ii) MD assessed by one expert reviewer evaluating percent density
(iii) 1092 women 40 to 60 years old with recent 2 years screening mammogram
Inverse

Bérubé et al. [32]Calcium containing foods**2005(i) 777 premenopausal and 783 post-menopausal women
(ii) Food frequency questionnaire for estimation of dietary intake
(iii) MD assessed by computer-assisted method
Inverse

Masala et al. [33]Cheese ad dietary calcium2006(i) 2,000 women with mammogram taken 5 years after enrollment in the EPIC-Florence study
(ii) Original mammograms retrieved
(iii) Information on dietary habits collected during 5 years
(iv) MD assessed according to Wolfe's classification
Inverse

Takata et al. [34]Dairy products2007(i) 3512 mammograms from 1250 premenopausal and postmenopausal women
(ii) MD assessed by computer-assisted method
(iii) Validated food frequency questionnaire for estimation of dietary intake
None

Thomson et al. [10]Dairy products2007(i) Cross-sectional design
(ii) MD assessed by computer-assisted method
(iii) Arizona food frequency questionnaire for estimation of dietary intake
Inverse

Mishra et al. [35]Dietary calcium from childhood 2008(i) cohort of 1161 women followed up since their birth
(ii) documentation of diet at age 4 by 24 h recalls and at age 36, 43 and 53 by 5-day food records
(iii) MD assessed by computer-assisted method
None***

Wu et al.**** [17]Sunlight2013(i) 650 premenopausal women
(ii) validated sunlight exposure questionnaire via telephone
(iii) MD classified according to Tabar’s classification
Inverse

Peplonska et al. [36]Sunlight2012(i) cross-sectional study
(ii) Investigating whether rotating night shift working in nurses was associated with MD
(iii) 640 nurses and midwives 40 to 60 years
(iv) MD assessed by computer-assisted method
None

López et al. [19]Physical inactivity2003(i) information collected from the Chicago Breast Health Project
(ii) evaluation of association of hours of daily physical inactivity
(iii) MD assessed quantitatively
(iv) 294 Hispanic women
None*****

Suijkerbuijk et al. [37]Physical inactivity2006(i) cross-sectional study
(ii) 620 women 49 to 68 years, participants of the Dutch Prospect-European Prospective Investigation into Cancer and Nutrition cohort
(iii) self-administered questionnaire about duration and intensity of physical activity
(iv) MD assessed by computer-assisted system
None

Siozon et al. [38]Recreational physical activity2006(i) 375 white and African American women
(ii) Structured questionnaire obtaining data from 5 time periods of activity: menarche to 1st screening mammography, first 3 and 10 years after menarche, the most recent 10 years and the 3 years prior to mammogram screening
None

Samimi et al. [39]Recent physical activity2008(i) cross-sectional study
(ii) 1,398 women in the Nurses' Health Study
(iii) three groupings: premenopausal, postmenopausal without HRT, postmenopausal currently under HRT
(iv) MD assessed by computer-assisted method
(v) prospectively collected questionnaires
None

Oestreicher et al. [40]Physical activity2008Cohort of pre- and early perimenopausal women of 4 different ethnicitiesNon-significant inverse

Woolcott et al. [41]Aerobic exercise2010(i) inside the ALPHA trial: randomized controlled trial
(ii) 320 postmenopausal, sedentary women 50 to 74 years
(iii) randomized to 45 minutes, 5 days per week aerobic exercise or control with usual life-style for 1 year
(iv) MD assessed by computer-assisted system
None

Conroy et al. [18]Physical activity2010(i) using longitudinal data from 1996 to 2004
(ii) multiethnic cohort of 722 pre- and early perimenopausal women participating in the Study of Women's Health Across the Nation
None

Marmara et al. [42]Last five years recreational physical activity2011(i) cross-sectional study
(ii) 724 women 45–67 years
(iii) interview-administered questionnaire
(iv) MD classified according to BIRAD classification
Inverse

Qureshi et al. [43]Physical activity2012(i) women data from the Norwegian Breast Cancer Screening Program
(ii) MD assessed by computer-assisted system
(iii) 2218 postmenopausal women 50–69
(iv) 13-page questionnaire
None******

Pub yr: Publication year, **primarily dairy products, ***except for a cross-sectional inverse association at age 53 years in post-menopausal women, ****They showed that sunlight exposure in childhood is more effective, *****MD slightly higher when 3.5 hr physical inactivity per day, ******probable inverse association in overweight women.