1,4-Dihydropyridine Calcium Channel Blockers: Homology Modeling of the Receptor and Assessment of Structure Activity Relationship

<table>Sequence alignment between the amino acid sequence of model and that of KcsA. Red lines are chain break, dashes are inserted gabs, color code: blue = identical, sky blue = similar (color intensity decreases with similarity decrease), and white = no similarity; model = DHP receptor model amino acid sequence; 2A9H = the amino acid sequence of the template KcsA; numbers from 1 to 480 are amino acid sequence ruler.</table>

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Figure 1

Figure 1: 1,4-Dihydropyridine Calcium Channel Blockers: Homology Modeling of the Receptor and Assessment of Structure Activity Relationship 