1,4-Dihydropyridine Calcium Channel Blockers: Homology Modeling of the Receptor and Assessment of Structure Activity Relationship
ProSA plot. Each repeat was examined separately. (a) ProSA Z-scores for DHP receptor model (left) template (right) and the complete PDB as a function of protein length. Blue and sky blue dots are Z-scores of PDB structures determined by X-ray crystallography and NMR, respectively; (b) ProSA energy profiles for DHP receptor model (four repeats) and (c) ProSA energy profiles for template (four repeats). Negative scores indicate a high quality model.
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