1,4-Dihydropyridine Calcium Channel Blockers: Homology Modeling of the Receptor and Assessment of Structure Activity Relationship
Figure 6
3D structure of DHP receptor model. (a) Superimposition between template (green) and the model of DHP receptor (red), line ribbon presentation; (b) C alpha stick presentation of 3D structure of DHP receptor model showing the two calcium ions position; (c) selectivity filter glutamate residues make salt bridge with calcium ions (green CPK style).
