International Scholarly Research Notices / 2014 / Article / Fig 8

Research Article

1,4-Dihydropyridine Calcium Channel Blockers: Homology Modeling of the Receptor and Assessment of Structure Activity Relationship

Figure 8

DHP receptor active site. (a) DHP sensing residues and calcium ion; (b) affinity axis passes through Try1149 (H-bond site) and Tyr1460 (ring to ring interaction site); chirality-activity axis (axis 2) passes through water lake and calcium and hydrophobic bracelet (Leu397, Leu745, Met 1185, and Ile1468).
203518.fig.008a
(a)
203518.fig.008b
(b)

Article of the Year Award: Outstanding research contributions of 2020, as selected by our Chief Editors. Read the winning articles.