1,4-Dihydropyridine Calcium Channel Blockers: Homology Modeling of the Receptor and Assessment of Structure Activity Relationship

<table class="table-group" id="tab2"><tr><td><table class="table"><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr class="thead"><td align="left">Items</td><td align="center">Model</td><td align="center">Template</td><td align="left">Comment</td></tr><tr><td class="thead-hr" colspan="4"><hr/></td></tr><tr><td align="left">ERRAT</td><td align="center">77.37</td><td align="center">86.24</td><td align="left">ERRAT overall quality factor</td></tr><tr><td align="left">ProSA</td><td align="center">−3.66</td><td align="center">−3.63</td><td align="left">ProSA Z-score as average of the four repeats</td></tr><tr><td align="left">Verify3D</td><td align="center">66.46% (W)</td><td align="center">69.39% (W)</td><td align="left">Percentage of residues with Verify3D average score &gt; 0.2; Verify3D overall assessment of the structure (P = pass, W = warning, or F = fail) shown in parentheses</td></tr><tr class="table-tr"><td colspan="4"><hr class="tbody-hr"/></td></tr></table></td></tr></table>

Assessment scores for the DHP receptor model compared to the template.

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Table 2

Table 2: 1,4-Dihydropyridine Calcium Channel Blockers: Homology Modeling of the Receptor and Assessment of Structure Activity Relationship 