Formulation Development and Optimization of Fast Dissolving Tablets of Aceclofenac Using Natural Superdisintegrant

Table 1

Design layout of 3² factorial design.

Formulation batches	𝑋1	𝑋2
D1	−1	−1
D2	0	−1
D3	+1	−1
D4	−1	0
D5	0	0
D6	+1	0
D7	−1	+1
D8	0	+1
D9	+1	+1

Where 1 is the high value, −1 is the low value, and 0 is the centre value for the factors 𝑋₁ and 𝑋₂.
𝑋₁: amount of β-cyclodextrine.
𝑋₂: amount of Lepidium sativum mucilage.