Research Article
Formulation Development and Optimization of Fast Dissolving Tablets of Aceclofenac Using Natural Superdisintegrant
Table 2
Composition of 32 factorial design batches of Aceclofenac fast dissolving tablets.
| Ingredients (mg) | D1 | D2 | D3 | D4 | D5 | D6 | D7 | D8 | D9 |
| Aceclofenac | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | 100 | β-CD | 0 | 15 | 30 | 0 | 15 | 30 | 0 | 15 | 30 | Lepidium Sativum Mucilage | 6 | 6 | 6 | 15 | 15 | 15 | 24 | 24 | 24 | MCC | 144 | 129 | 114 | 135 | 120 | 105 | 126 | 111 | 96 | Mannitol | 30 | 30 | 30 | 30 | 30 | 30 | 30 | 30 | 30 | Aspartame | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | 10 | Talc | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | 4 | Magnesium Stearate | 6 | 6 | 6 | 6 | 6 | 6 | 6 | 6 | 6 |
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MCC: microcrystalline cellulose, β-CD: β-cyclodextrine.
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