Formulation Development and Optimization of Fast Dissolving Tablets of Aceclofenac Using Natural Superdisintegrant

Table 4

Evaluation of postcompression parameters of factorial design batches of Aceclofenac fast dissolving tablets.

Parameters	D1	D2	D3	D4	D5	D6	D7	D8	D9
Hardness (kg/cm^2)	2.0	2.5	3.0	2.0	2.5	3.0	2.0	2.5	3.0
Friability (%)	0.9	0.62	0.31	0.9	0.65	0.33	0.9	0.68	0.38
Disintegration time (sec)	22	25	26	20	15	22	19	20	30
In vitro dispersion time (sec)	31	24	38	24	21	29	20	36	34
Wetting time (sec)	29	26	31	24	18	28	21	25	38
Water absorption ratio (%)	91.7	131	132	126	134	135	128	129	122

Data are represented as mean ± SD (𝑛=3).