Simultaneous Estimation of Paracetamol, Ambroxol Hydrochloride, Levocetirizine Dihydrochloride, and Phenylephrine Hydrochloride in Combined Tablet Formulation by First-Order Derivative Spectrophotometry
Table 2
Recovery data for the proposed method.
Drug
Amount present (μg/mL)*
Amount added (μg/mL)*
Amount estimated (μg/mL)*
Amount recovered (μg/mL)*
Percentage recovered ()*
% RSD
PARA
59.6533
47.3221
107.8898
48.2365
101.93
0.2757
59.6533
60.0016
119.3033
59.6500
99.41
0.2891
59.6533
71.8727
131.4650
71.8117
99.92
0.1703
AMB
12.1440
9.6417
21.6966
9.5526
99.08
0.4154
12.1440
12.0892
24.2021
12.0581
99.74
0.3285
12.1440
14.3880
26.3979
14.2539
99.07
0.7261
LEVO
12.1176
9.5284
21.6460
9.5284
100.00
0.3518
12.1176
12.0916
23.9843
11.8667
98.14
0.3848
12.1176
14.3880
26.3683
14.2507
99.05
0.4868
PHEN
11.9592
9.5524
21.6182
9.6590
101.11
0.9930
11.9592
12.1304
24.2703
12.3111
101.49
0.6889
11.9592
14.3957
26.5306
14.5714
101.22
0.7734
Mean of six observations. RSD: relative standard deviation.
