Review Article

Oral Cavity as an Extragastric Reservoir of Helicobacter pylori

Table 5

Data regarding the coinfection of H. pylori and oral infection.

No.AuthorsYearMethod used to detect H. pylori Sample sizePrevalence of coinfection of H. pylori

1Agarwal and Jithendra [31]2012PCR-16S rRNA30 H. pylori positive and 20 H. pylori negative patientsOverall-36%; in H. pylori positive group-60%
2Agarwal and Jithendra [31]2012Culture30 H. pylori positive and 20 H. pylori patientsOverall-18%; in H. pylori positive group-30%
3Bago et al. [41]2011PCR-16S rDNA56 patients with chronic periodontitis and gastric H. pylori positive37.5%
4Silva et al. [58]2010PCR-16S rRNA115 patientsOverall-8.7%; among H. pylori positive group-14.93%
5Eskandari et al. [56]2010PCR-16S rRNA67 patients with chronic periodontitis-23 with H. pylori positive gastritisOverall-5.97%; among H. pylori positive group-17.39%
6Al Asqah et al. [35]2009RUT62 dyspeptic patients with periodontitis and 39 dyspeptic patients without periodontitisOverall-32.7%; 66% among H. pylori positive patients
7Liu et al. [61]2009PCR-860-bp fragment443 dyspeptic patientsOverall-42.7%; among H. pylori positive subjects-69.2% (75.5% in 18–29 years; 61.7% in 30–39 years; 79.7% in 40–49 years; 76.6% in ≥50 years)
8Leszczyńska
et al. [27]
2009EIA164 dyspeptic patients referred for endoscopy-95 H. pylori positive and 69 noninfectedOverall-47.6%; 82.1% in H. pylori positive
9Silva et al. [59]2009PCR-16s ribosomal and cagA genes30 with H. pylori positive with gastric disease and 32 with H. pylori positive with no gastric diseaseOverall-17.7%. Among cases, H. pylori DNA detected in 36.6%, and cagA gene detected in 3 out of 11 samples. In control group-0%
10Bürgers et al. [36]2008PCR-16S rDNA94 patients who underwent upper gastrointestinal endoscopyOverall-1.1% 3.5% of H. pylori positive subjects
11Teoman et al. [25]2007PCR-Urease A67 dyspeptic patientsOverall-25.4%; among H. pylori positive group-36.2%
12Anand et al. [38]2006RUTSixty-five dyspeptic patients with H. pylori infection and 69 dyspeptic patients without H. pylori infection Overall-43.3%; 89.2% among cases
13 Chitsazi et al. [23]2006RUT88 dyspeptic patients-44 with H. pylori infection and 44 without H. pylori infectionOverall 34.1%; 36.4% in H. pylori positive group
14Agüloğlu et al. [76]2006CLO test468 patients who were H. pylori positive by CLO test25.2%
15Agüloğlu et al. [76]2006EIA318 patients who were H. pylori positive by EIA23.6%
16Agüloğlu et al. [76]2006Culture295 patients who were H. pylori positive by culture14.6%
17Czesnikiewicz-Guzik et al. [75]2005Culture100 female patients6.9%
18 Kignel et al. [64]2005PCR-16S rRNA49 dyspeptic patients2% of the total population and 5% of H. pylori positive subjects
19Umeda et al. [37]2003PCR-16S rRNA56 dental patientsOverall-14.3%; among H. pylori positive group-28.6%.
20 Gürbüz et al. [30]2003RUT75 dyspeptic patientsOverall-81.3%; among H. pylori positive subjects-93.9%
21Berroteran et al. [39]2002PCR-Urease genes32 dyspeptic patients and 20 asymptomatic controlsOverall-13.5%; 58% among dyspeptic patients
22Suk et al. [45] 2002PCR-cagA65 patients with dyspeptic symptoms Overall-43.1%, 73.7% among H. pylori positive patients
23Suk et al. [45] 2002RUT65 patients with dyspeptic symptoms Overall-58.5%, 100% among H. pylori positive patients
24Özdemir et al. [49]2001CLO test81 dyspeptic patientsOverall-64.2%; among H. pylori positive group-82.5%.
25Song et al. [70]2000PCR-860-bp fragment21 patientsOverall-47.6%; among H. pylori positive group-100%
26Qureshi et al. [50]1999CLO test60 dyspeptic patientsOverall 33.3%; in H. pylori positive 55.6%
27Oshowo et al. [32]1998PCR-16S rRNA and culture208 dyspeptic patients-116 H. pylori positive and 92 H. pylori negativeBy PCR-Overall 6.25%; in H. pylori positive-11.2%
By culture-Overall 1%; in H. pylori positive-1.7% By both methods-Overall 7.2% in H. pylori positive-12.9%.
28Hardo et al. [24]199516S rRNA62 dyspeptic patients0
29Mapstone et al. [72]1993PCR-16S rRNA21 dyspeptic patients-13 with H. pylori associated gastritis and 8 who had normal histology15.4% in gastritis group-overall prevalence 9.5%
30 Nguyen et al. [73]1993PCR-16S rRNA25 dyspeptic patientsOverall 28%, among H. pylori positive individuals 38.8%
31Krajden et al. [16]1989Culture71 patients undergoing endoscopy1.4% of the total population and 3.5% of H. pylori positive subjects