Research Article

Potential Interaction of Green Tea Extract with Hydrochlorothiazide on Diuretic Activity in Rats

Table 2

Effect on electrolyte excretion in urine.

TreatmentElectrolyte concentration (mmol/L)
Na+K+

Normal control
HCTZ120.82 ± 4.45***63.83 ± 2.29**
GTE-10071.39 ± 3.81**51.29 ± 2.34
GTE-50095.83 ± 3.56**
GTE-100 + HCTZ138.92 ± 3.83***#51.48 ± 3.193#
GTE-500 + HCTZ159.39 ± 4.39***##46.52 ± 2.32##

All values are mean ± SEM, , , when compared to normal control; , compared to hydrochlorothiazide. GTE-100 (green tea extract, 100 mg/kg), GTE-500 (green tea extract, 500 mg/kg), and HCTZ (hydrochlorothiazide, 10 mg/kg).